Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impact of HLA alloimmunization in gene-modified autologous stem cell transplant for transfusion-dependent thalassemia

16 Mar 2025

Abstract excerpt

ABSTRACT: We report our single-center experience demonstrating that HLA class I alloimmunization predicts longer time to platelet engraftment, increased bleeding complications, and higher transfusion requirements in patients undergoing gene-modified hematopoietic stem cell transplant for transfusion-dependent β thalassemia.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood groups and transfusion
Share to Hematopoietic Stem Cell Transplantation
Share to Immunodeficiency and Autoimmune Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40089998
DOI: 10.1182/blood.2024027034

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact of HLA alloimmunization in gene-modified autologous stem cell transplant for transfusion-dependent thalassemiaPMID 40089998Read ↗

Genotyping and the Future of Transfusion in Sickle Cell Disease.Semantic proximity Read ↗

Gene Therapy in Patients with Transfusion-Dependent β-Thalassemia.Semantic proximity Read ↗

Gene therapy in transfusion-dependent non-β0/β0 genotype β-thalassemia: first real-world experience of beti-cel.Semantic proximity Read ↗

Betibeglogene Autotemcel Gene Therapy for Non-β0/β0 Genotype β-Thalassemia.Semantic proximity Read ↗

Modified lentiviral globin gene therapy for pediatric β0/β0 transfusion-dependent β-thalassemia: A single-center, single-arm pilot trialSemantic proximity Read ↗

Allogeneic stem cell transplantation for thalassemia majorSemantic proximity Read ↗

Lentiglobin Gene Therapy for Transfusion-Dependent β-Thalassemia: Update from the Northstar Hgb-204 Phase 1/2 Clinical StudySemantic proximity Read ↗

Beyond HLA: an exploratory pilot study of non-HLA antibodies, HLA sensitization, and GSTT1 genotype in platelet transfusion refractoriness.Semantic proximity Read ↗

Intrabone hematopoietic stem cell gene therapy for adult and pediatric patients affected by transfusion-dependent ß-thalassemiaSemantic proximity Read ↗

Impact of β-globin mutations on outcome of matched related donor hematopoietic stem cell transplantation for patients with β-thalassemia major.Semantic proximity Read ↗

Rh alloimmunization in chronically transfused patients with thalassemia receiving RhD, C, E, and K matched transfusionsSemantic proximity Read ↗

Unrelated donor stem cell transplantation in adult patients with thalassemiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.