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Assessing Microsatellite Variations in Plasmodium falciparum Following a Decade-Long Antimalaria Campaign in Kenya.

Molecular ecology - 1 Apr 2025

Hemming-Schroeder Elizabeth, Hubbard Alfred, Ebhodaghe Faith I, Vorontsova Tatiana, Zhong Daibin, Zhou Guofa, Lo Eugenia, Atieli Harrysone, Githeko Andrew, Kazura James W, Yan Guiyun

Abstract excerpt

Anti-malaria interventions typically reduce the intensity of Plasmodium transmission, but the effects of reduced transmission on P. falciparum population biology remain unclear. Highly polymorphic microsatellite markers in P. falciparum were used to investigate genetic diversity, polyclonality and genetic structure among populations in areas of varying malaria transmission intensity across Kenya. We also assessed...

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PMID: 40087832
DOI: 10.1111/mec.17713
PMCID: PMC11936721

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