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Exploring the Causal Relationship Between Gut Microbiota and Pulmonary Artery Hypertension: Insights From Mendelian Randomization

13 Mar 2025

Abstract excerpt

Background Research into the “gut–lung” axis links gut microbiota to pulmonary artery hypertension (PAH). However, the mechanisms by which gut microbiota influence PAH remain unclear. We aimed to investigate the causal relationship between the gut microbiota and PAH using Mendelian randomization analysis, identify key microbiota and metabolites, and explore the regulatory role of associated genes in PAH...

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Share to Chronic Obstructive Pulmonary Disease (COPD) Research
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PMID: 40079338
DOI: 10.1161/jaha.124.038150

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