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Prognosis and Phenotypes of Advanced Head and Neck Carcinoma Associated With Hypercalcemia.

Head & neck - 1 Aug 2025

Mamou Elodie, Gougis Paul, Abbar Baptiste, Spano Jean-Philippe, Morardet Laetitia, Vozy Aurore

Abstract excerpt

PURPOSE: Hypercalcemia is the most common metabolic disorder in cancer, affecting 10%-20% of patients with advanced malignancies, including squamous cell carcinoma of the head and neck (HNSCC), though its prognostic significance remains poorly studied. This study aimed to evaluate the prognostic impact of hypercalcemia at diagnosis in patients with locally advanced or metastatic HNSCC and to explore underlying...

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Identifiers

PMID: 40067281
DOI: 10.1002/hed.28126
PMCID: PMC12248268

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