Article
Asthma Phenotype Can Be Influenced by Recurrent Respiratory Infections in Patients with Primary Antibody Deficiency: The Impact of Ig Therapy.
Respiration; international review of thoracic diseases - 1 Jan 2025
Vivarelli Emanuele, Perlato Margherita, Accinno Matteo, Brugnoli Barbara, Milanese Maria Elena, Cataudella Edoardo, Licci Giuseppe, Maggiore Giandomenico, Rossi Oliviero, Parronchi Paola, Cosmi Lorenzo, Vultaggio Alessandra, Matucci Andrea
Abstract excerpt
INTRODUCTION: Asthma is a heterogeneous chronic inflammatory disease involving different underling pathogenetic mechanisms. We aimed to investigate the characteristics of patients with the diagnosis of asthma and primary antibody immunodeficiency (PAD) and the impact of immunoglobulin therapy (IVIg). METHODS: Thirty-three patients with severe asthma and PAD (either IgG subclasses deficiency or unclassified...
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