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PM2.5 constituent exposures and maternal circulatory homocysteine in early pregnancy

7 Mar 2025

Abstract excerpt

Elevated homocysteine (Hcy) is a pathogenic mechanism of adverse pregnancy outcomes and PM 2.5 –induced cardiovascular diseases. We investigated the associations of fine particulate matter (PM 2.5 ) and chemical constituent exposures with maternal circulatory Hcy in early pregnancy. Serum Hcy and 5-methyltetrahydrofolate in 324 women with pregnancy (162 normal early pregnancy [NEP] and 162 early pregnancy loss...

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PMID: 40055787
DOI: 10.1186/s12940-025-01160-z

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