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Multi-omics clustering analysis carries out the molecular-specific subtypes of thyroid carcinoma: implicating for the precise treatment strategies.

Genes and immunity - 1 Apr 2025

Wang Zhenglin, Han Qijun, Hu Xianyu, Wang Xu, Sun Rui, Huang Siwei, Chen Wei

Abstract excerpt

Thyroid cancer (TC) is the most prevalent endocrine malignancy worldwide. This study aimed to explore the molecular subtypes and improve the selection of targeted therapies. We used multi-omics data from 539 patients with DNA methylation, gene mutations, mRNA, lncRNA, and miRNA expressions. This study employed consensus clustering algorithms to identify molecular subtypes and used various bioinformatics tools to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40038532
DOI: 10.1038/s41435-025-00322-w

Genes

CXCL17

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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