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Decoding Osteosarcoma’s Lactylation Gene Expression: Insights Into Prognosis, Immune Dynamics, and Treatment

1 Jan 2025

Abstract excerpt

Osteosarcoma (OS), characterized by a complex tumor microenvironment, poses challenges in treatment, metastasis, and therapy resistance. This study examined the impact of lactylation, a posttranslational modification, on gene expression and tumor behavior in OS, particularly its influence on prognosis, immune cell infiltration, and chemotherapy response. Utilizing data from the Gene Expression Omnibus series...

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PMID: 40026531
DOI: 10.1155/ancp/6517238

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