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Article

Cellular immune breadth of an Omicron-specific, self-amplifying monovalent mRNA vaccine booster for COVID-19

1 Mar 2025

Abstract excerpt

Selecting a booster vaccine strategy that generates cellular immune breadth is crucial for effectively recalling cellular reservoirs upon infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants. This post hoc analysis from a multicentre, randomized phase 3 study (CTRI/2022/10/046475) compared the cellular immune breadth induced by self-replicating mRNA (samRNA) vaccine GEMCOVAC-OM,...

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PMID: 40025095
DOI: 10.1038/s41541-025-01076-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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