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Article

Circulating miR-126-3p is a mechanistic biomarker for knee osteoarthritis

27 Feb 2025

Abstract excerpt

Osteoarthritis is a major contributor to pain and disability worldwide, yet there are currently no validated soluble biomarkers or disease-modifying treatments. Given that microRNAs are promising mechanistic biomarkers that can be therapeutically targeted, in this study, we aimed to identify and prioritize reproducible circulating microRNAs associated with radiographic knee osteoarthritis. Across four independent...

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PMID: 40016267
DOI: 10.1038/s41467-025-57308-5

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