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Comparative phenotypic and genotypic antimicrobial susceptibility surveillance in Achromobacter spp. through whole genome sequencing.

Microbiology spectrum - 1 Apr 2025

Ray Sreejana, Flemming Laurie K, Scudder Chelsea J, Ly Melissa A, Porterfield Harry S, Smith Richard D, Clark Andrew E, Johnson J Kristie, Das Sanchita

Abstract excerpt

Treatment of Achromobacter infections remains challenging due to intrinsic and acquired resistance to commonly used antimicrobial agents and no established clinical breakpoints. We attempted accurate species-level identification and compared the presence of genotypic resistance markers to phenotypic susceptibility patterns in retrospectively collected clinical isolates of Achromobacter spp. Our study concludes...

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Identifiers

PMID: 40013782
DOI: 10.1128/spectrum.02527-24
PMCID: PMC11960112

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