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Healthcare provider-mediated cascade testing of Lynch syndrome to at-risk family members: an interview study.

Familial cancer - 26 Feb 2025

Ong Serene, Chua Zi Yang, Yuen Jeanette, Chiang Jianbang, Zewen Zhang, Ngeow Joanne, Lysaght Tamra

Abstract excerpt

Cascade testing is often recommended for cancer predisposition syndromes, like Lynch syndrome (LS), to identify at-risk family members. The uptake of cascade testing is typically meditated by the proband's willingness to disclose their results with family members. Of which, cascade testing uptake rates in Singapore has been low, compared to global rates. Studies suggest that healthcare providers (HCPs)-meditated...

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PMID: 40011264
DOI: 10.1007/s10689-025-00450-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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