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Article

Down-regulation of PCK2 enhanced the radioresistance phenotype of nasopharyngeal carcinoma.

International journal of radiation biology - 1 Jan 2025

He Yijun, Yan Li, Zhang Ruiqi, Yang Rui, Kong Zhaolu, Wang Xiaosheng

Abstract excerpt

PURPOSE: Radiotherapy is the main treatment for non-distant metastatic nasopharyngeal carcinoma (NPC). However, about 15% of NPC patients still experience local tumor recurrence after radiotherapy. The mechanisms underlying the radioresistance of NPC have not been fully understood. This study explored the role of phosphoenolpyruvate carboxykinase2 (PCK2) in NPC radiosensitivity. METHODS: Two NPC cell lines,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 40009793
DOI: 10.1080/09553002.2025.2470226

Genes

PCK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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