Article
Multiple features of cell-free mtDNA for predicting transarterial chemoembolization response in hepatocellular carcinoma.
Hepatology communications - 1 Mar 2025
Dang Miao, Wang Siyuan, Peng Fan, Zhang Runjiao, Jiao Huanmin, Zhang Huanqin, Dong Haiying, Zhang Hongxin, Xing Jinliang, Guo Xu, Liu Yang
Abstract excerpt
BACKGROUND: Transarterial chemoembolization (TACE) is the primary treatment modality for advanced HCC, yet its efficacy assessment and prognosis prediction largely depend on imaging and serological markers that possess inherent limitations in terms of real-time capability, sensitivity, and specificity. Here, we explored whether multiple features of cell-free mitochondrial DNA (cf-mtDNA), including copy number,...
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