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Article

The effects of coagulation factors on the risk of autoimmune diseases: A Mendelian randomization study.

Medicine - 27 Dec 2024

Li Shuxuan, Zhou Chunlei, Li Wenjing, Kang Lichun, Mu Hong

Abstract excerpt

The objective of this study was to investigate the potential causal relationship between coagulation factors and autoimmune diseases (ADs). We employed Mendelian randomization to investigate the associations between selected 7 coagulation factors and 10 ADs, leveraging genetic variants as instrumental variables to assess causal relationships between exposures of interest and outcomes. Within the scope of this...

Read the complete abstract on PubMed

Topics

Humans
Mendelian Randomization Analysis
Autoimmune Diseases
Blood Coagulation Factors
Risk Factors
Fibrinogen

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Factor VIII

Polymorphism, Single Nucleotide

Genetic Predisposition to Disease

Source

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Identifiers

PMID: 39969330
DOI: 10.1097/MD.0000000000040893
PMCID: PMC11688059

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