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Comprehensive bioinformatic analysis reveals prognostic significance and functional insights of candidate gene expression in colorectal cancer

15 Feb 2025

Abstract excerpt

The purpose of this study was to investigate biomarkers associated with poor clinical outcomes in colorectal cancer (CRC) by utilizing comprehensive datasets from the gene expression omnibus (GEO) databases GSE41258, GSE39582, and GSE44861. We initially identified differentially expressed genes (DEGs) and applied weighted gene co-expression network analysis (WGCNA) to the GSE41258 dataset to reveal key gene...

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PMID: 39955350
DOI: 10.1038/s41598-025-90025-z

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