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Machine Learning for Classifying Tuberculosis Drug-Resistance from DNA Sequencing Data

1 Dec 2017

Abstract excerpt

MOTIVATION: Correct and rapid determination of Mycobacterium tuberculosis (MTB) resistance against available tuberculosis (TB) drugs is essential for the control and management of TB. Conventional molecular diagnostic test assumes that the presence of any well-studied single nucleotide polymorphisms is sufficient to cause resistance, which yields low sensitivity for resistance classification. METHODS: Given the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29240876
DOI: 10.1093/bioinformatics/btx801

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