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Understanding microRNA-Mediated Chemoresistance in Colorectal Cancer Treatment

29 Jan 2025

Abstract excerpt

Colorectal cancer (CRC) remains the second most lethal cancer worldwide, with incidence rates expected to rise substantially by 2040. Although biomarker-driven therapies have improved treatment, responses to standard chemotherapeutics, such as 5-fluorouracil (5-FU), oxaliplatin, and irinotecan, vary considerably. This clinical heterogeneity emphasizes the urgent need for novel biomarkers that can guide...

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PMID: 39940936
DOI: 10.3390/ijms26031168

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