Article
Sperm oxidative damage acquired during seminal plasma removal for assisted reproductive technology is reduced by BGP-15
11 Feb 2025
Abstract excerpt
PURPOSE: Semen manipulation for assisted reproductive technology (ART) causes spermatozoa damage; thus, we investigated the potential of the novel therapeutic BGP-15 to preserve sperm quality during semen washing prior to insemination. METHODS: Donated human ejaculates (N = 40), with or without 10 µM BGP-15, were analyzed for sperm motility, DNA fragmentation, and oxidation. Seminal plasma was removed using...
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