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Exploring the Associations of Obesity and Glycemic Traits with Retinal Vein Occlusion: A Univariate and Multivariable Mendelian Randomization Study.

Ophthalmic epidemiology - 1 Oct 2025

Yuan Weichen, Xu Xin, Zhang Xiran, Fan Wenqi, Zhou Wenkai, Zhao Fangkun

Abstract excerpt

PURPOSE: To explore the genetic links between obesity, glycemic traits and retinal vein occlusion (RVO). METHODS: Summary-level statistics for obesity and glycemic traits were extracted from publicly available genome-wide association studies (GWAS) of European participants in the IEU Open GWAS database. Genetic associations with clinically diagnosed RVO were obtained from the FinnGenresearch project (372 cases...

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PMID: 39919303
DOI: 10.1080/09286586.2025.2458245

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