Article
Sex-Specific Association between Anatomic Variants of the Circle of Willis and Intracranial Aneurysms in Individuals with a Familial Predisposition.
AJNR. American journal of neuroradiology - 1 Aug 2025
Nanninga Marloes H A, van Strien Denise A M, Velthuis Birgitta K, Velthuis Mireille R E, Vos Iris N, Groenheide Phebe J, Ruigrok Ynte M, van der Schaaf Irene C
Abstract excerpt
BACKGROUND AND PURPOSE: First-degree relatives of patients with aneurysmal subarachnoid hemorrhage (aSAH) face elevated risks for intracranial aneurysm development and aSAH, which both occur more often in women. Anatomic variants of the circle of Willis (CoW) affect its hemodynamics and are associated with unruptured intracranial aneurysms (UIAs). It is unknown if these findings apply to patients with a familial...
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