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Article

Correlation between Circle of Willis configuration and intracranial arterial dolichoectasia, and genetic contributions.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association - 1 Nov 2024

Feng Lu, Yang Xin-Zhuang, Zhang Ding-Ding, Zhai Fei-Fei, Li Ming-Li, Zhou Li-Xin, Ni Jun, Yao Ming, Jin Zheng-Yu, Cui Li-Ying, Zhang Shu-Yang, Han Fei, Zhu Yi-Cheng

Abstract excerpt

OBJECTIVES: Intracranial arterial dolichoectasia (IADE) is characterized by the dilation, elongation, and tortuosity of intracranial arteries. We aimed to investigate the association between variations of the Circle of Willis (COW) and IADE in the general population, as well as estimate the genetic correlation between COW variations and IADE. METHODS: A total of 981 individuals from a population-based cohort were...

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PMID: 39179190
DOI: 10.1016/j.jstrokecerebrovasdis.2024.107955

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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