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Evaluation of plasmid pBI143 for its optimal concentration methods, seasonal impact, and potential as a normalization parameter in wastewater-based epidemiology

31 Jan 2025

Abstract excerpt

Plasmid pBI143, abundant in the human gut, is a promising human-specific fecal marker. However, studies on its optimal concentration methods, seasonal variations, and potential as a normalization parameter for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), remain limited. Among the three concentration methods compared, polyethylene glycol...

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PMID: 39893813
DOI: 10.1016/j.scitotenv.2025.178661

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