Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

EXO1 is a key gene for lung-resident memory T cells and has diagnostic and predictive values for lung adenocarcinoma.

Scientific reports - 1 Feb 2025

Li Zhuoqi, Lin Xiaoyan, Yang Yuanhui, Tian Mei, Zhang Lu, Huang Fujing, Wen Xiao, Wei Zhigang, Tian Yuan

Abstract excerpt

Lung adenocarcinoma (LUAD) is a very common and lethal kind of lung malignancy. An increasing number of studies indicated that tissue-resident memory T (TRM) cells played significant roles in anti-cancer immunity. In our previous study, EXO1 was found to be a core gene for TRM cells in the prognosis of LUAD. However, the roles of EXO1 in the tumor microenvironment, and its application in the diagnosis and...

Topics

Join the communities discussing this publication.

Adenocarcinoma of Lung
Biomarkers, Tumor
DNA Methylation
DNA Repair Enzymes
Exodeoxyribonucleases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Expression Regulation, Neoplastic

Tumor Microenvironment

Source

Open in PubMed Open full text

Identifiers

PMID: 39893221
DOI: 10.1038/s41598-025-88126-w
PMCID: PMC11787328

Genes

EXO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

EXO1 is a key gene for lung-resident memory T cells and has diagnostic and predictive values for lung adenocarcinoma.PMID 39893221Read ↗

Identification of EXO1 as a potential biomarker associated with prognosis and tumor immune microenvironment for specific human cancers.Semantic proximity Read ↗

Exonuclease 1 (EXO1) is a Potential Prognostic Biomarker and Correlates with Immune Infiltrates in Lung AdenocarcinomaSemantic proximity Read ↗

Signatures of Multi-Omics Reveal Distinct Tumor Immune Microenvironment Contributing to Immunotherapy in Lung AdenocarcinomaSemantic proximity Read ↗

Aggressive early-stage lung adenocarcinoma is characterized by epithelial cell plasticity with acquirement of stem-like traits and immune evasion phenotype.Semantic proximity Read ↗

Construction of immune-related and prognostic lncRNA clusters and identification of their immune and genomic alterations characteristics in lung adenocarcinoma samples.Semantic proximity Read ↗

TOX correlates with prognosis, immune infiltration, and T cells exhaustion in lung adenocarcinoma.Semantic proximity Read ↗

An Investigation of the Immune Microenvironment and Genome during Lung Adenocarcinoma DevelopmentSemantic proximity Read ↗

Long Non-Coding RNAs in Lung Cancer: The Role in Tumor MicroenvironmentSemantic proximity Read ↗

IER5L is a Prognostic Biomarker in Pan-Cancer Analysis and Correlates with Immune Infiltration and Immune Molecules in Non-Small Cell Lung CancerSemantic proximity Read ↗

Identification of N7-methylguanosine related signature for prognosis and immunotherapy efficacy prediction in lung adenocarcinomaSemantic proximity Read ↗

Comprehensive Analysis of the Function, Immune Profiles, and Clinical Implication of m1A Regulators in Lung AdenocarcinomaSemantic proximity Read ↗

A Novel Prognostic Model of Early-Stage Lung Adenocarcinoma Integrating Methylation and Immune BiomarkersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.