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Unraveling the role of autophagy regulation in Crohn's disease: from genetic mechanisms to potential therapeutics

21 Mar 2024

Abstract excerpt

Autophagy serves as the primary intracellular degradation mechanism in which damaged organelles and self-cytoplasmic proteins are transported to the lysosome for degradation. Crohn's disease, an idiopathic chronic inflammatory disorder of the gastrointestinal tract, manifests in diverse regions of the digestive system. Recent research suggests that autophagy modulation may be a new avenue for treating Crohn's...

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PMID: 39883213
DOI: 10.1007/s44307-024-00021-z

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