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Maternal seafood intake, dietary contaminant exposure, and risk of juvenile idiopathic arthritis: exploring gene-environment interactions.

Frontiers in immunology - 1 Jan 2024

Dåstøl Vilde Øverlien, Haftorn Kristine Løkås, Rudsari Hamid Khoshfekr, Jaholkowski Piotr Pawel, Størdal Ketil, Håberg Siri Eldevik, Weinberg Clarice R, Rider Lisa G, Andreassen Ole A, Brantsæter Anne Lise, Caspersen Ida Henriette, Sanner Helga

Abstract excerpt

Objectives: Juvenile idiopathic arthritis (JIA) originates from a complex interplay between genetic and environmental factors. We investigated the association between seafood intake and dietary contaminant exposure during pregnancy and JIA risk, to identify sex differences and gene-environment interactions. Methods: We used the Norwegian Mother, Father, and Child Cohort Study (MoBa), a population-based...

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Identifiers

PMID: 39877361
DOI: 10.3389/fimmu.2024.1523990
PMCID: PMC11772167

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