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Article

A multi-omic landscape of steatosis-to-NASH progression

1 Dec 2022

Abstract excerpt

Nonalcoholic steatohepatitis (NASH) has emerged as a major cause of liver failure and hepatocellular carcinoma. Investigation into the molecular mechanisms that underlie steatosis-to-NASH progression is key to understanding the development of NASH pathophysiology. Here, we present comprehensive multi-omic profiles of preclinical animal models to identify genes, non-coding RNAs, proteins, and plasma metabolites...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39872077
DOI: 10.1093/lifemeta/loac034

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