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Article

Essential Fatty Acids Interconversion in the Human Fetal Liver

18 Sept 2009

Abstract excerpt

In order to study the role played by the fetoplacental unit in providing the human fetus with arachidonic acid, delta 5- and delta 6-desaturase activities were studied in microsomes from human fetal liver and placenta after 18 and 22 weeks of gestation. We evidenced for the first time delta 5- and delta 6-desaturase activities in fetal liver microsomes. As in adult liver, delta 6-desaturation is the rate-limiting...

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PMID: 3986251
DOI: 10.1159/000242104

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