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Article

Sex-specific DNA methylation marks associated with sex-biased risk of recurrence in unprovoked venous thromboembolism.

Journal of thrombosis and haemostasis : JTH - 1 Apr 2025

Bezerra Ohanna C L, Rodger Marc, Munsch Gaëlle, Kovacs Michael J, Le Gal Grégoire, Morange Pierre-Emmanuel, Trégouët David-Alexandre, Greenwood Celia M T, Gagnon France

Abstract excerpt

BACKGROUND: Whether to stop oral anticoagulants after a first unprovoked venous thromboembolism (VTE) is challenging, partially due to an intriguingly higher risk of VTE recurrence (rVTE) in men after therapy discontinuation. DNA methylation (DNAm) differences between men and women might underlie this sex-biased rVTE risk difference. OBJECTIVES: To investigate sex-specific associations between DNAm at...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Epigenesis, Genetic

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Source

Identifiers

PMID: 39848545
DOI: 10.1016/j.jtha.2025.01.004

Genes

DENND3
DIP2B
TBC1D22B
ZHX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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