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Article

Current status and perspectives of hematopoietic cell transplantation in patients with paroxysmal nocturnal hemoglobinuria

7 Jan 2025

Abstract excerpt

Background: Paroxysmal nocturnal hemoglobinuria (PNH) is a rare complement-driven acquired hemolytic anemia with specific presentations of hemoglobinuria, abdominal pain, fatigue, and thrombosis. Objective: To review the current therapeutic strategies for PNH, including anti-complement therapy and allogeneic hematopoietic cell transplantation (alloHCT), focusing on the tailoring of the approach to the disease...

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Share to Coagulation, Bradykinin, Polyphosphates, and Angioedema
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Identifiers

PMID: 39840046
DOI: 10.3389/fimmu.2024.1521484

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