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Article

Calcium-mediated mitochondrial fission and mitophagy drive glycolysis to facilitate arterivirus proliferation

13 Jan 2025

Abstract excerpt

Mitochondria, recognized as the "powerhouse" of cells, play a vital role in generating cellular energy through dynamic processes such as fission and fusion. Viruses have evolved mechanisms to hijack mitochondrial function for their survival and proliferation. Here, we report that infection with the swine arterivirus porcine reproductive and respiratory syndrome virus (PRRSV), manipulates mitochondria calcium ions...

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PMID: 39804926
DOI: 10.1371/journal.ppat.1012872

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