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Article

Epigenetics and individuality: from concepts to causality across timescales.

Nature reviews. Genetics - 1 Jun 2025

Webster Amy K, Phillips Patrick C

Abstract excerpt

Traditionally, differences among individuals have been divided into genetic and environmental causes. However, both types of variation can underlie regulatory changes in gene expression - that is, epigenetic changes - that persist across cell divisions (developmental differentiation) and even across generations (transgenerational inheritance). Increasingly, epigenetic variation among individuals is recognized as...

Topics

Humans
Epigenesis, Genetic
Genetic Variation
Phenotype
Animals
Individuality
Epigenomics

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 39789149
DOI: 10.1038/s41576-024-00804-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-39789149-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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