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CASP5 associated with PANoptosis promotes tumorigenesis and progression of clear cell renal cell carcinoma

8 Jan 2025

Abstract excerpt

Clear cell renal cell carcinoma (ccRCC) is a globally severe cancer with an unfavorable prognosis. PANoptosis, a form of cell death regulated by PANoptosomes, plays a role in numerous cancer types. However, the specific roles of genes associated with PANoptosis in the development and advancement of ccRCC remain unclear. Our study developed a risk model utilizing three PANoptosis-associated genes (Caspase 4...

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PMID: 39780201
DOI: 10.1186/s12935-024-03630-9

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