Selection Can Favor a Recombination Landscape That Limits Polygenic Adaptation.

Abstract excerpt

Modifiers of recombination rates have been described but the selective pressures acting on them and their effect on adaptation to novel environments remain unclear. We performed experimental evolution in the nematode Caenorhabditis elegans using alternative rec-1 alleles modifying the position of meiotic crossovers along chromosomes without detectable direct fitness effects. We show that adaptation to a novel...

Topics

• Animals
• Caenorhabditis elegans
• Selection, Genetic
• Recombination, Genetic
• Multifactorial Inheritance
• Alleles
• Adaptation, Biological