Article
Highly proliferating cancer cells function as novel prognostic biomarkers for lung adenocarcinoma with particular usefulness for stage IA risk stratification.
BMC cancer - 7 Jan 2025
Xiong Yanlu, Ma Yongfu, Lei Jie, Zhu Jianfei, Xie Nianlin, Tian Feng, Lu Qiang, Wen Miaomiao, Zheng Qian, Han Yong, Jiang Tao, Liu Yang
Abstract excerpt
BACKGROUND: The refinement of risk stratification in lung adenocarcinoma (LUAD) plays a pivotal role in advancing precision medicine; however, the current staging classification falls short of comprehensiveness, particularly in the case of stage IA patients. We aimed to molecularly stratify LUAD patients especially for stage IA. METHODS: We analysed tumour heterogeneity and identified highly proliferating cancer...
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