Article
Paratesticular/inguinal SMARCB1 / INI1 deficient carcinomas with yolk sac tumour‐like differentiation are aggressive somatic malignancies
6 Jan 2025
Abstract excerpt
AIMS: Extragonadal yolk sac tumour (YST) is rare, and may present a diagnostic challenge. YST differentiation was recently reported in some somatically derived tumours in the sinonasal location and in the female genital tract, together with a SMARCB1/INI1 loss. We report two paratesticular/inguinal tumours with striking morphological and immunohistochemical similarities with YST, further expanding the spectrum of...
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