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Article

Presence of liver metastasis correlated with high tumor abundance and indicated adverse prognostic feature in EGFR mutation non-small-cell lung cancer patients.

Scientific reports - 2 Jan 2025

Sitthideatphaiboon Piyada, Simseekeaw Pronwasun, Teerapakpinyo Chinachote, Zungsontiporn Nicha, Chintanapakdee Wariya, Itthisawatpan Itthi, Shuangshoti Shanop, Sriuranpong Virote, Tongbai Thanisa, Vinayanuwattikun Chanida

Abstract excerpt

EGFR-TKIs are effective therapies for non-small cell lung cancer (NSCLC) patients with EGFR-activating mutations. However, responses vary within individuals and resistant disease inevitably emerges. A prospective cohort of 130 patients with advanced EGFR mutation NSCLC were enrolled. Pre-and post-treatment plasma from subjects treated with EGFR-TKIs were obtained. The correlation between EGFR mutation abundance...

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Aged, 80 and over
Carcinoma, Non-Small-Cell Lung
ErbB Receptors
Liver Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein Kinase Inhibitors

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PMID: 39747343
DOI: 10.1038/s41598-024-83930-2
PMCID: PMC11696231

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