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Assessment of MGMT and TERT Subtypes and Prognosis of Glioblastoma by Whole Tumor Apparent Diffusion Coefficient Histogram Analysis.

Brain and behavior - 1 Jan 2025

Chen Ling, Wu Min, Li Yao, Tang Lifang, Tang Chuyun, Huang Lizhao, Li Tao, Zhu Li

Abstract excerpt

BACKGROUND: Adult glioblastomas (GBMs) are associated with high recurrence and mortality. Personalized treatment based on molecular markers may help improve the prognosis. We aimed to evaluate whether apparent diffusion coefficient (ADC) histogram analysis can better predict MGMT and TERT molecular characteristics and to determine the prognostic relevance of genetic profile in patients with GBM. MATERIALS AND...

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Identifiers

PMID: 39739534
DOI: 10.1002/brb3.70175
PMCID: PMC11686090

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