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Construction and forensic genetic characterization of 11 autosomal haplotypes consisting of 22 tri-allelic indels.

Forensic science international. Genetics - 1 May 2018

Zhao Xiaohong, Chen Xiaogang, Zhao Yuancun, Zhang Shu, Gao Zehua, Yang Yiwen, Wang Yufang, Zhang Ji

Abstract excerpt

Insertion/deletion polymorphisms (indels), which combine the advantages of both short tandem repeats and single-nucleotide polymorphisms, are suitable for parentage testing. To overcome the limitations of the low polymorphism of di-allelic indels, we constructed a set of haplotypes with physically linked, multi-allelic indels. Candidate haplotypes were selected from the 1000 Genomes Project database, and were...

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PMID: 29428890
DOI: 10.1016/j.fsigen.2018.02.001

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