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Faecal metaproteomics analysis reveals a high cardiovascular risk profile across healthy individuals and heart failure patients

22 Dec 2024

Abstract excerpt

The gut microbiota is a crucial link between diet and cardiovascular disease (CVD). Using fecal metaproteomics, a method that concurrently captures human gut and microbiome proteins, we determined the crosstalk between gut microbiome, diet, gut health, and CVD. Traditional CVD risk factors (age, BMI, sex, blood pressure) explained < 10% of the proteome variance. However, unsupervised human protein-based...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39709554
DOI: 10.1080/19490976.2024.2441356

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