Article
The Gut Microbiome Contributes to a Substantial Proportion of the Variation in Blood Lipids.
Circulation research - 9 Oct 2015
Fu Jingyuan, Bonder Marc Jan, Cenit María Carmen, Tigchelaar Ettje F, Maatman Astrid, Dekens Jackie A M, Brandsma Eelke, Marczynska Joanna, Imhann Floris, Weersma Rinse K, Franke Lude, Poon Tiffany W, Xavier Ramnik J, Gevers Dirk, Hofker Marten H, Wijmenga Cisca, Zhernakova Alexandra
Abstract excerpt
RATIONALE: Evidence suggests that the gut microbiome is involved in the development of cardiovascular disease, with the host-microbe interaction regulating immune and metabolic pathways. However, there was no firm evidence for associations between microbiota and metabolic risk factors for cardiovascular disease from large-scale studies in humans. In particular, there was no strong evidence for association between...
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