Identification of a genomic cluster related to hypersecretion of intestinal mucus and mucinolytic activity of atypical enteropathogenic Escherichia coli (aEPEC).

doi:10.3389/fcimb.2024.1393369

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Identification of a genomic cluster related to hypersecretion of intestinal mucus and mucinolytic activity of atypical enteropathogenic Escherichia coli (aEPEC).

Frontiers in cellular and infection microbiology - 1 Jan 2024

Trovão Liana de Oliveira, Vieira Mônica Aparecida Midolli, Santos Ana Carolina de Mello, Puño-Sarmiento Juan Josue, Nunes Pedro Henrique Soares, Santos Fernanda Fernandes, Rocha Victória Galdino Pavlenco, Knöbl Terezinha, Navarro-Garcia Fernando, Gomes Tânia Aparecida Tardelli

Abstract excerpt

Enteropathogenic Escherichia coli (EPEC) strains are subdivided into typical (tEPEC) and atypical (aEPEC) according to the presence or absence of a virulence-associated plasmid called pEAF. Our research group has previously demonstrated that two aEPEC strains, 0421-1 and 3991-1, induce an increase in mucus production in a rabbit ileal loop model in vivo. This phenomenon was not observed with a tEPEC prototype...

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PMID: 39703371
DOI: 10.3389/fcimb.2024.1393369
PMCID: PMC11656320

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