Article
Analysis of the virulence of an atypical enteropathogenic Escherichia coli strain in vitro and in vivo and the influence of type three secretion system.
BioMed research international - 1 Jan 2014
Sampaio Suely C F, Moreira Fabiana C, Liberatore Ana M A, Vieira Mônica A M, Knobl Terezinha, Romão Fabiano T, Hernandes Rodrigo T, Ferreira Claudete S A, Ferreira Antônio P, Felipe-Silva Aloísio, Sinigaglia-Coimbra Rita, Koh Ivan H J, Gomes Tania A T
Abstract excerpt
Atypical enteropathogenic Escherichia coli (aEPEC) inject various effectors into intestinal cells through a type three secretion system (T3SS), causing attaching and effacing (A/E) lesions. We investigated the role of T3SS in the ability of the aEPEC 1711-4 strain to interact with enterocytes in vitro (Caco-2 cells) and in vivo (rabbit ileal loops) and to translocate the rat intestinal mucosa in vivo. A T3SS...
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