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Article

DF-MDA: An effective diffusion-based computational model for predicting miRNA-disease association.

Molecular therapy : the journal of the American Society of Gene Therapy - 7 Apr 2021

Li Hao-Yuan, You Zhu-Hong, Wang Lei, Yan Xin, Li Zheng-Wei

Abstract excerpt

It is reported that microRNAs (miRNAs) play an important role in various human diseases. However, the mechanisms of miRNA in these diseases have not been fully understood. Therefore, detecting potential miRNA-disease associations has far-reaching significance for pathological development and the diagnosis and treatment of complex diseases. In this study, we propose a novel diffusion-based computational method,...

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Identifiers

PMID: 33429082
DOI: 10.1016/j.ymthe.2021.01.003
PMCID: PMC8058487

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