Article
APEX-based proximity labeling in Plasmodium identifies a membrane protein with dual functions during mosquito infection
18 Dec 2024
Abstract excerpt
Transmission of the malaria parasite Plasmodium to mosquitoes necessitates gamete egress from red blood cells to allow zygote formation and ookinete motility to enable penetration of the midgut epithelium. Both processes are dependent on the secretion of proteins from distinct sets of specialized vesicles. Inhibiting some of these proteins has shown potential for blocking parasite transmission to the mosquito. To...
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