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Signal peptide and N-glycosylation of N-terminal-CD2v determine the hemadsorption of African swine fever virus

28 Sept 2023

Abstract excerpt

ABSTRACT African swine fever virus (ASFV) is the cause of African swine fever (ASF), a devastating disease that affects domestic pigs and wild boar and is currently responsible for the largest animal epidemic. One of the characteristics of ASFV infection, but absent in naturally attenuated strains, is hemadsorption (HAD), a phenomenon that has been linked to virulence. In this study, we have shown that ASFV HAD...

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PMID: 37768082
DOI: 10.1128/jvi.01030-23

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