Article
Role of Annexin 7 (ANXA7) as a Tumor Suppressor and a Regulator of Drug Resistance in Thyroid Cancer.
International journal of molecular sciences - 9 Dec 2024
Bera Alakesh, Radhakrishnan Surya, Puthillathu Narayanan, Subramanian Madhan, Gana Nahbuma, Russ Eric, Pollard Harvey B, Srivastava Meera
Abstract excerpt
Thyroid cancer is the most common endocrine malignancy in the United States, with an overall favorable prognosis. However, some patients experience poor outcomes due to the development of resistance to conventional therapies. Genetic alterations, including mutations in BRAF, Met, and p53, play critical roles in thyroid cancer progression, with the BRAF V600E mutation detected in over 60% of cases. This study...
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