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Article

MiRNA-34a, miRNA-145, and miRNA-222 Expression, Matrix Metalloproteinases, TNF-α and VEGF in Patients with Different Phenotypes of Coronary Artery Disease.

International journal of molecular sciences - 3 Dec 2024

Iusupova Alfiya Oskarovna, Pakhtusov Nikolay Nikolaevich, Slepova Olga Alexandrovna, Khabarova Natalia Vladimirovna, Privalova Elena Vitalievna, Bure Irina Vladimirovna, Nemtsova Marina Vyacheslavovna, Belenkov Yuri Nikitich

Abstract excerpt

The development of different phenotypes of coronary artery (CA) lesions is regulated via many various factors, such as pro-inflammatory agents, zinc-dependent endopeptidases, growth factors and circulating microRNAs (miRs). To evaluate the expression levels of miR-34a, miR-145 and miR-222, tumor necrosis factor α (TNF-α), matrix metalloproteinases (MMP-1, -9, -13 and -14) and vascular endothelial growth factor...

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PMID: 39684689
DOI: 10.3390/ijms252312978
PMCID: PMC11641108

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