Aberrant Positions of the Chemosensory Neurons in the Neurotransmitter-Release Mutant unc-13.

Abstract excerpt

Secretion of neurotransmitter- and neuropeptide-containing vesicles is a regulated process orchestrated by multiple proteins. Of these, mutants, defective in the unc-13 and unc-31 genes, responsible for neurotransmitter and neuropeptide release, respectively, are routinely used to elucidate neural and circuitry functions. While these mutants result in severe functional deficits, their neuroanatomy is assumed to...

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