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Mechanism and Clinical Application Prospects of Mitochondrial DNA Single Nucleotide Polymorphism in Neurodegenerative Diseases.

Neurochemical research - 14 Dec 2024

Xu Mengying, Li Tianjiao, Liu Xuan, Islam Binish, Xiang Yuyue, Zou Xiyan, Wang Jianwu

Abstract excerpt

Mitochondrial dysfunction is well recognized as a critical component of the complicated pathogenesis of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and Huntington's disease. This review investigates the influence of mitochondrial DNA single nucleotide polymorphisms on mitochondrial function, as well as their role in the onset and progression of these neurodegenerative diseases....

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PMID: 39673588
DOI: 10.1007/s11064-024-04311-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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